Role and New Insights of Pirfenidone in Fibrotic Diseases

Pirfenidone (PFD) is a non-peptide synthetic molecule issued as a broad-spectrum anti-fibrotic drug with the ability to decrease TGF-β1, TNF-α, PDGF and COL1A1 expression, which is highly related to prevent or remove excessive deposition of scar tissue in several organs. Basic and clinical evidence...

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Detalles Bibliográficos
Publicado en:Int J Med Sci
Autores principales: Lopez-de la Mora, David Alejandro, Sanchez-Roque, Cibeles, Montoya-Buelna, Margarita, Sanchez-Enriquez, Sergio, Lucano-Landeros, Silvia, Macias-Barragan, Jose, Armendariz-Borunda, Juan
Formato: Artigo
Lenguaje:Inglês
Publicado: Ivyspring International Publisher 2015
Materias:
Review
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643073/
https://ncbi.nlm.nih.gov/pubmed/26640402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.11579
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