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The multifaceted role of pirfenidone and its novel targets

BACKGROUND: Pirfenidone (PFD) is a molecule that exhibits antifibrotic properties in a variety of in vitro and animal models of lung, liver and renal fibrosis. These pathologies share many fibrogenic pathways with an abnormal fibrous wound-healing process; consequently, tissue repair and tissue rege...

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Detalhes bibliográficos
Main Authors: Macías-Barragán, José, Sandoval-Rodríguez, Ana, Navarro-Partida, Jose, Armendáriz-Borunda, Juan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944211/
https://ncbi.nlm.nih.gov/pubmed/20809935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-1536-3-16
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