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Pancreatic Digestive Enzyme Blockade in the Intestine Increases Survival After Experimental Shock
Shock, sepsis, and multiorgan failure are associated with inflammation, morbidity, and high mortality. The underlying pathophysiological mechanism is unknown, but evidence suggests that pancreatic enzymes in the intestinal lumen autodigest the intestine and generate systemic inflammation. Blocking t...
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| Vydáno v: | Sci Transl Med |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4643000/ https://ncbi.nlm.nih.gov/pubmed/23345609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3005046 |
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