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Pancreatic Digestive Enzyme Blockade in the Intestine Increases Survival After Experimental Shock
Shock, sepsis, and multiorgan failure are associated with inflammation, morbidity, and high mortality. The underlying pathophysiological mechanism is unknown, but evidence suggests that pancreatic enzymes in the intestinal lumen autodigest the intestine and generate systemic inflammation. Blocking t...
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| Pubblicato in: | Sci Transl Med |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4643000/ https://ncbi.nlm.nih.gov/pubmed/23345609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3005046 |
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