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Determination of RNA polymerase binding surfaces of transcription factors by NMR spectroscopy

In bacteria, RNA polymerase (RNAP), the central enzyme of transcription, is regulated by N-utilization substance (Nus) transcription factors. Several of these factors interact directly, and only transiently, with RNAP to modulate its function. As details of these interactions are largely unknown, we...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Drögemüller, Johanna, Strauß, Martin, Schweimer, Kristian, Jurk, Marcel, Rösch, Paul, Knauer, Stefan H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642336/
https://ncbi.nlm.nih.gov/pubmed/26560741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16428
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