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G Protein-Coupled Receptors Directly Bind Filamin A with High Affinity and Promote Filamin Phosphorylation

[Image: see text] Although interaction of a few G protein-coupled receptors (GPCRs) with Filamin A, a key actin cross-linking and biomechanical signal transducer protein, has been observed, a comprehensive structure–function analysis of this interaction is lacking. Through a systematic sequence-base...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Tirupula, Kalyan C., Ithychanda, Sujay S., Mohan, Maradumane L., Naga Prasad, Sathyamangla V., Qin, Jun, Karnik, Sadashiva S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2015
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642222/
https://ncbi.nlm.nih.gov/pubmed/26460884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00975
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