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A Mechanism of Global Shape-dependent Recognition and Phosphorylation of Filamin by Protein Kinase A
Protein phosphorylation mediates essentially all aspects of cellular life. In humans, this is achieved by ∼500 kinases, each recognizing a specific consensus motif (CM) in the substrates. The majority of CMs are surface-exposed and are thought to be accessible to kinases for phosphorylation. Here we...
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| 出版年: | J Biol Chem |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4375502/ https://ncbi.nlm.nih.gov/pubmed/25666618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.633446 |
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