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Recent Advances in Engineering Microbial Rhodopsins for Optogenetics
Protein engineering of microbial rhodopsins has been successful in generating variants with improved properties for applications in optogenetics. Members of this membrane protein family can act as both actuators and sensors of neuronal activity. Chimeragenesis, structure-guided mutagenesis, and dire...
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| Udgivet i: | Curr Opin Struct Biol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4641784/ https://ncbi.nlm.nih.gov/pubmed/26038227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2015.05.001 |
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