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Recent Advances in Engineering Microbial Rhodopsins for Optogenetics

Protein engineering of microbial rhodopsins has been successful in generating variants with improved properties for applications in optogenetics. Members of this membrane protein family can act as both actuators and sensors of neuronal activity. Chimeragenesis, structure-guided mutagenesis, and dire...

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Detalhes bibliográficos
Publicado no:Curr Opin Struct Biol
Main Authors: McIsaac, R. Scott, Bedbrook, Claire N., Arnold, Frances H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641784/
https://ncbi.nlm.nih.gov/pubmed/26038227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2015.05.001
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