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SUMOylation of sPRDM16 promotes the progression of acute myeloid leukemia
BACKGROUND: In addition to genetic and epigenetic alteration, post-translational modification of proteins plays a critical role in the initiation, progression and maturation of acute myeloid leukemia (AML). METHODS: The SUMOylation site of sPRDM16 at K568 was mutated to arginine by site-directed mut...
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Publicado no: | BMC Cancer |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4641379/ https://ncbi.nlm.nih.gov/pubmed/26559765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1844-2 |
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