Overexpression of sPRDM16 coupled with loss of p53 induces myeloid leukemias in mice

Transgenic expression of the abnormal products of acute myeloid leukemia–associated (AML-associated) primary chromosomal translocations in hematopoietic stem/progenitor cells initiates leukemogenesis in mice, yet additional mutations are needed for leukemia development. We report here aberrant expre...

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מידע ביבליוגרפי
Main Authors: Shing, Danielle C., Trubia, Maurizio, Marchesi, Francesco, Radaelli, Enrico, Belloni, Elena, Tapinassi, Cinzia, Scanziani, Eugenio, Mecucci, Cristina, Crescenzi, Barbara, Lahortiga, Idoya, Odero, Maria D., Zardo, Giuseppe, Gruszka, Alicja, Minucci, Saverio, Di Fiore, Pier Paolo, Pelicci, Pier Giuseppe
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Clinical Investigation 2007
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2082144/
https://ncbi.nlm.nih.gov/pubmed/18037989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32390
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