FLT3-ITD cooperates with inv(16) to promote progression to acute myeloid leukemia

The inversion of chromosome 16 in the inv(16)(p13q22) is one of the most frequent cytogenetic abnormalities observed in acute myeloid leukemia (AML). The inv(16) fuses the core binding factor (CBF) beta subunit with the coiled-coil rod domain of smooth muscle myosin heavy chain (SMMHC). Expression o...

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Detalhes bibliográficos
Main Authors: Kim, Hyung-Gyoon, Kojima, Kyoko, Swindle, C. Scott, Cotta, Claudiu V., Huo, Yongliang, Reddy, Vishnu, Klug, Christopher A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2214774/
https://ncbi.nlm.nih.gov/pubmed/17967943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-06-030312
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