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Neuroprotective effects of urate are mediated by augmenting astrocytic glutathione synthesis and release

Urate has emerged as a promising target for neuroprotection based on epidemiological observations, preclinical models, and early clinical trial results in multiple neurologic diseases, including Parkinson's disease (PD). This study investigates the astrocytic mechanism of urate's neuroprot...

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Bibliografiska uppgifter
I publikationen:Neurobiol Dis
Huvudupphovsmän: Bakshi, Rachit, Zhang, Hong, Logan, Robert, Joshi, Ila, Xu, Yuehang, Chen, Xiqun, Schwarzschild, Michael A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641017/
https://ncbi.nlm.nih.gov/pubmed/26341543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2015.08.022
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