Neuroprotective effects of urate are mediated by augmenting astrocytic glutathione synthesis and release

Urate has emerged as a promising target for neuroprotection based on epidemiological observations, preclinical models, and early clinical trial results in multiple neurologic diseases, including Parkinson's disease (PD). This study investigates the astrocytic mechanism of urate's neuroprot...

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Bibliografiske detaljer
Udgivet i:Neurobiol Dis
Main Authors: Bakshi, Rachit, Zhang, Hong, Logan, Robert, Joshi, Ila, Xu, Yuehang, Chen, Xiqun, Schwarzschild, Michael A.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641017/
https://ncbi.nlm.nih.gov/pubmed/26341543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2015.08.022
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