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Protection of dopaminergic cells by urate requires its accumulation in astrocytes

Urate is the end product of purine metabolism and a major antioxidant circulating in humans. Recent data link higher levels of urate with a reduced risk of developing Parkinson’s disease (PD) and with a slower rate of its progression. In this study, we investigated the role of astrocytes in urate-in...

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Detalhes bibliográficos
Main Authors: Cipriani, Sara, Desjardins, Cody A., Burdett, Thomas C., Xu, Yuehang, Xu, Kui, Schwarzschild, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438313/
https://ncbi.nlm.nih.gov/pubmed/22671773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2012.07820.x
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