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Langerhans Cells Facilitate UVB-induced Epidermal Carcinogenesis
Ultraviolet B (UVB) light is considered the major environmental inducer of human keratinocyte DNA mutations, including within the tumor-suppressor gene p53, and chronic exposure is associated with cutaneous squamous cell carcinoma (SCC) formation. Langerhans cells (LC) comprise a dendritic network w...
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| Veröffentlicht in: | J Invest Dermatol |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4640962/ https://ncbi.nlm.nih.gov/pubmed/26053049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2015.207 |
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