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Langerhans Cells Facilitate Epithelial DNA Damage and Squamous Cell Carcinoma
Polyaromatic hydrocarbons (PAHs) are prevalent, potent carcinogens, and 7,12-dimethylbenz[a]anthracene (DMBA) is a model PAH widely used to study tumorigenesis. Mice lacking Langerhans cells (LCs), a signatory epidermal dendritic cell (DC), are protected from cutaneous chemical carcinogenesis, indep...
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| Main Authors: | , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3753811/ https://ncbi.nlm.nih.gov/pubmed/22223807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1211600 |
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