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The Rac1 Exchange Factor Dock5 Is Essential for Bone Resorption by Osteoclasts

Osteoporosis, which results from excessive bone resorption by osteoclasts, is the major cause of morbidity for elder people. Identification of clinically relevant regulators is needed to develop novel therapeutic strategies. Rho GTPases have essential functions in osteoclasts by regulating actin dyn...

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Vydáno v:J Bone Miner Res
Hlavní autoři: Vives, Virginie, Laurin, Mélanie, Cres, Gaelle, Larrousse, Pauline, Morichaud, Zakia, Noel, Danièle, Côté, Jean-François, Blangy, Anne
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640905/
https://ncbi.nlm.nih.gov/pubmed/21542010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.282
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