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The Rac1 Exchange Factor Dock5 Is Essential for Bone Resorption by Osteoclasts

Osteoporosis, which results from excessive bone resorption by osteoclasts, is the major cause of morbidity for elder people. Identification of clinically relevant regulators is needed to develop novel therapeutic strategies. Rho GTPases have essential functions in osteoclasts by regulating actin dyn...

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Detalles Bibliográficos
Publicado en:J Bone Miner Res
Main Authors: Vives, Virginie, Laurin, Mélanie, Cres, Gaelle, Larrousse, Pauline, Morichaud, Zakia, Noel, Danièle, Côté, Jean-François, Blangy, Anne
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640905/
https://ncbi.nlm.nih.gov/pubmed/21542010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.282
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