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The atypical Rac activator Dock180 (Dock1) regulates myoblast fusion in vivo

Dock1 (also known as Dock180) is a prototypical member of a new family of atypical Rho GTPase activators. Genetic studies in Drosophila and Caenorhabditis elegans have demonstrated that Dock1 orthologues in these organisms have a crucial role in activating Rac GTPase signaling. We generated mutant a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Laurin, Mélanie, Fradet, Nadine, Blangy, Anne, Hall, Alan, Vuori, Kristiina, Côté, Jean-François
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2563090/
https://ncbi.nlm.nih.gov/pubmed/18820033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805546105
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