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Targeted binding of nucleocapsid protein transforms the folding landscape of HIV-1 TAR RNA
Retroviral nucleocapsid (NC) proteins are nucleic acid chaperones that play a key role in the viral life cycle. During reverse transcription, HIV-1 NC facilitates the rearrangement of nucleic acid secondary structure, allowing the transactivation response (TAR) RNA hairpin to be transiently destabil...
Gardado en:
| Publicado en: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4640786/ https://ncbi.nlm.nih.gov/pubmed/26483503 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1510100112 |
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