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Structure of an RNA polymerase II preinitiation complex

The structure of a 33-protein, 1.5-MDa RNA polymerase II preinitiation complex (PIC) was determined by cryo-EM and image processing at a resolution of 6–11 Å. Atomic structures of over 50% of the mass were fitted into the electron density map in a manner consistent with protein–protein cross-links p...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Murakami, Kenji, Tsai, Kuang-Lei, Kalisman, Nir, Bushnell, David A., Asturias, Francisco J., Kornberg, Roger D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640751/
https://ncbi.nlm.nih.gov/pubmed/26483468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1518255112
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