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The structural and functional effects of the familial hypertrophic cardiomyopathy-linked cardiac troponin C mutation, L29Q

Familial hypertrophic cardiomyopathy (FHC) is characterized by severe abnormal cardiac muscle growth. The traditional view of disease progression in FHC is that an increase in the Ca(2 +)-sensitivity of cardiac muscle contraction ultimately leads to pathogenic myocardial remodeling, though recent st...

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Detalhes bibliográficos
Publicado no:J Mol Cell Cardiol
Main Authors: Robertson, Ian M., Sevrieva, Ivanka, Li, Monica X., Irving, Malcolm, Sun, Yin-Biao, Sykes, Brian D.
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640586/
https://ncbi.nlm.nih.gov/pubmed/26341255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2015.08.017
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