Loading...

A structural and functional perspective into the mechanism of Ca(2+)-sensitizers that target the cardiac troponin complex

The Ca(2+) dependant interaction between troponin I (cTnI) and troponin C (cTnC) triggers contraction in heart muscle. Heart failure is characterized by a decrease in cardiac output, and compounds that increase the sensitivity of cardiac muscle to Ca(2+) have therapeutic potential. The Ca(2+)-sensit...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Robertson, Ian M., Sun, Yin-Biao, Li, Monica X., Sykes, Brian D.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975748/
https://ncbi.nlm.nih.gov/pubmed/20801130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2010.08.019
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!