Poly-arginine and arginine-rich peptides are neuroprotective in stroke models

Using cortical neuronal cultures and glutamic acid excitotoxicity and oxygen-glucose deprivation (OGD) stroke models, we demonstrated that poly-arginine and arginine-rich cell-penetrating peptides (CPPs), are highly neuroprotective, with efficacy increasing with increasing arginine content, have the...

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Pubblicato in:J Cereb Blood Flow Metab
Autori principali: Meloni, Bruno P, Brookes, Laura M, Clark, Vince W, Cross, Jane L, Edwards, Adam B, Anderton, Ryan S, Hopkins, Richard M, Hoffmann, Katrin, Knuckey, Neville W
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640246/
https://ncbi.nlm.nih.gov/pubmed/25669902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2015.11
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