HSPB1 as a Novel Regulator of Ferroptotic Cancer Cell Death

Ferroptosis is an iron-dependent form of non-apoptotic cell death, but its molecular mechanism remains largely unknown. Here, we demonstrate that heat shock protein beta-1 (HSPB1) is a negative regulator of ferroptotic cancer cell death. Erastin, a specific ferroptosis-inducing compound, stimulates...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Sun, Xiaofang, Ou, Zhanhui, Xie, Min, Kang, Rui, Fan, Yong, Niu, Xiaohua, Wang, Haichao, Cao, Lizhi, Tang, Daolin
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640181/
https://ncbi.nlm.nih.gov/pubmed/25728673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.32
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