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IL-21R signaling is critical for induction of spontaneous experimental autoimmune encephalomyelitis
IL-17–producing CD4(+) T cells (Th17 cells) have well-described pathogenic roles in tissue inflammation and autoimmune diseases, such as experimental autoimmune encephalomyelitis (EAE); however, the involvement of IL-21 in these processes has remained controversial. While IL-21 is an essential autoc...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4639966/ https://ncbi.nlm.nih.gov/pubmed/26413871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI75933 |
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