IL-21R signaling is critical for induction of spontaneous experimental autoimmune encephalomyelitis

IL-17–producing CD4(+) T cells (Th17 cells) have well-described pathogenic roles in tissue inflammation and autoimmune diseases, such as experimental autoimmune encephalomyelitis (EAE); however, the involvement of IL-21 in these processes has remained controversial. While IL-21 is an essential autoc...

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Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Asıl Yazarlar: Lee, Youjin, Mitsdoerffer, Meike, Xiao, Sheng, Gu, Guangxiang, Sobel, Raymond A., Kuchroo, Vijay K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4639966/
https://ncbi.nlm.nih.gov/pubmed/26413871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI75933
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