Development of 1-N-(11)C-Methyl-l- and -d-Tryptophan for pharmacokinetic imaging of the immune checkpoint inhibitor 1-Methyl-Tryptophan

1-Methyl-tryptophan (1MTrp) is known as a specific inhibitor targeting the immune- checkpoint protein indoleamine-2,3-dioxygenase, in two stereoisomers of levorotary (l) and dextrorotary (d). A long-standing debate exists in immunology and oncology: which stereoisomer has the potential of antitumor...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Xie, Lin, Maeda, Jun, Kumata, Katsushi, Yui, Joji, Zhang, Yiding, Hatori, Akiko, Nengaki, Nobuki, Wakizaka, Hidekatsu, Fujinaga, Masayuki, Yamasaki, Tomoteru, Shimoda, Yoko, Higuchi, Makoto, Suhara, Tetsuya, Wang, Feng, Zhang, Ming-Rong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4639751/
https://ncbi.nlm.nih.gov/pubmed/26552594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16417
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi