Multicomponent reaction-based synthesis and biological evaluation of tricyclic heterofused quinolines with multi-trypanosomatid activity

Human African trypanosomiasis (HAT), Chagas disease and leishmaniasis, which are caused by the trypanosomatids Trypanosoma brucei, Trypanosoma cruzi and Leishmania species, are among the most deadly neglected tropical diseases. The development of drugs that are active against several trypanosomatids...

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Sparad:
Bibliografiska uppgifter
I publikationen:Eur J Med Chem
Huvudupphovsmän: Di Pietro, Ornella, Vicente-García, Esther, Taylor, Martin C., Berenguer, Diana, Viayna, Elisabet, Lanzoni, Anna, Sola, Irene, Sayago, Helena, Riera, Cristina, Fisa, Roser, Clos, M. Victòria, Pérez, Belén, Kelly, John M., Lavilla, Rodolfo, Muñoz-Torrero, Diego
Materialtyp: Artigo
Språk:Inglês
Publicerad: Editions Scientifiques Elsevier 2015
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4638191/
https://ncbi.nlm.nih.gov/pubmed/26479031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2015.10.007
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