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An EGFR/Src-dependent β4 integrin/FAK complex contributes to malignancy of breast cancer

β4 integrin and focal adhesion kinase (FAK) are often associated with a poor prognosis in cancer patients, and their signaling events have recently been linked to malignant outcomes. Here, we demonstrate, for the first time, physical and functional interactions between β4 integrin and FAK that influ...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tai, Yu-Ling, Chu, Pei-Yu, Lai, I-Rue, Wang, Ming-Yang, Tseng, Hui-Yuan, Guan, Jun-Lin, Liou, Jun-Yang, Shen, Tang-Long
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637903/
https://ncbi.nlm.nih.gov/pubmed/26549523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16408
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