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Integrin β5 contributes to the tumorigenic potential of breast cancer cells through Src-FAK and MEK-ERK signaling pathways

Cancer progression, response to therapy and metastasis depend on tumor microenvironment. Integrins are cell adhesion receptors that mediate interactions of cells with extracellular matrix (ECM). The αv-β-family of integrins contributes to tumorigenesis, response to therapy and cancer-stem cell biolo...

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Detalhes bibliográficos
Main Authors: Bianchi-Smiraglia, Anna, Paesante, Silvia, Bakin, Andrei V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481019/
https://ncbi.nlm.nih.gov/pubmed/22824793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.320
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