Discordant intracellular and plasma D-2-hydroxyglutarate levels in a patient with IDH2 mutated angioimmunoblastic T-cell lymphoma

Objectives: Angioimmunoblastic T-cell lymphoma (AITL) is an aggressive peripheral T-cell lymphoma with mutations in genes encoding isocitrate dehydrogenase1 and 2 (IDH1 and IDH2). Mutant IDH generates the oncometabolite D-2-hydroxyglutarate (D-2HG). We report the first case of discordant intracellul...

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Publicado en:Int J Clin Exp Pathol
Autores principales: Churchill, Hywyn, Naina, Harris, Boriack, Richard, Rakheja, Dinesh, Chen, Weina
Formato: Artigo
Lenguaje:Inglês
Publicado: e-Century Publishing Corporation 2015
Materias:
Case Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637738/
https://ncbi.nlm.nih.gov/pubmed/26617922
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