USP17-mediated deubiquitination and stabilization of HDAC2 in cigarette smoke extract-induced inflammation

Histone deacetylase HDAC2 regulates genes transcription via removing the acetyl group from histones. Glucocorticoids, the most potent anti-inflammatory treatment available for inflammatory diseases, inhibit the expression of inflammatory genes by recruiting HDAC2 to activated genes. In the lungs of...

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Bibliographic Details
Published in:Int J Clin Exp Pathol
Main Authors: Song, Huihui, Tao, Lianqin, Chen, Chen, Pan, Lina, Hao, Jimin, Ni, Yingmeng, Li, Dan, Li, Bin, Shi, Guochao
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2015
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637596/
https://ncbi.nlm.nih.gov/pubmed/26617781
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