E-Cadherin Expression in Obesity-Associated, Kras-initiated Pancreatic Ductal Adenocarcinoma in Mice

BACKGROUND: The epithelial-mesenchymal transition (EMT) is critical in the development of invasive epithelial malignancies. EMT is accelerated by inflammation, and results in decreased E-cadherin expression. Diet-induced obesity is an inflammatory state that accelerates pancreatic carcinogenesis; it...

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Bibliografiset tiedot
Julkaisussa:Surgery
Päätekijät: Stark, Alexander P., Chang, Hui-Hua, Jung, Xiaoman, Moro, Aune, Hertzer, Kathleen, Xu, Mu, Schmidt, Andrea, Hines, O. Joe, Eibl, Guido
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637247/
https://ncbi.nlm.nih.gov/pubmed/26297056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2015.07.023
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