Housing temperature-induced stress is suppressing murine GVHD through β2-adrenergic receptor signaling

Graft-versus-host disease (GVHD) is the major complication of allogeneic hematopoietic cell transplantation (alloHCT), a potentially curative therapy for hematologic diseases. It has long been thought that murine bone marrow (BM) derived T cells do not mediate severe GVHD because of their quantity a...

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Veröffentlicht in:J Immunol
Hauptverfasser: Leigh, Nicholas D., Kokolus, Kathleen M., O’Neill, Rachel E., Du, Wei, Eng, Jason W.-L., Qiu, Jingxin, Chen, George L., McCarthy, Philip L., Farrar, J. David, Cao, Xuefang, Repasky, Elizabeth A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637222/
https://ncbi.nlm.nih.gov/pubmed/26459348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500700
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