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NK Cell Proliferation Induced by IL-15 Transpresentation Is Negatively Regulated by Inhibitory Receptors

IL-15 bound to the IL-15 receptor α chain (IL-15Rα) is presented in trans to cells bearing the IL-2 receptor β and γ(c) chains. As IL-15 transpresentation occurs in the context of cell-to-cell contacts, it has the potential for regulation by and of other receptor–ligand interactions. In this study,...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Anton, Olga M., Vielkind, Susina, Peterson, Mary E., Tagaya, Yutaka, Long, Eric O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637193/
https://ncbi.nlm.nih.gov/pubmed/26453750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500414
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