Glucose Oxidase Induces Cellular Senescence in Immortal Renal Cells through ILK by Downregulating Klotho Gene Expression

Cellular senescence can be prematurely induced by oxidative stress involved in aging. In this work, we were searching for novel intermediaries in oxidative stress-induced senescence, focusing our interest on integrin-linked kinase (ILK), a scaffold protein at cell-extracellular matrix (ECM) adhesion...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Troyano-Suárez, Nuria, del Nogal-Avila, María, Mora, Inés, Sosa, Patricia, López-Ongil, Susana, Rodriguez-Puyol, Diego, Olmos, Gemma, Ruíz-Torres, María Piedad
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637093/
https://ncbi.nlm.nih.gov/pubmed/26583057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/416738
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