Glucose Oxidase Induces Cellular Senescence in Immortal Renal Cells through ILK by Downregulating Klotho Gene Expression

Cellular senescence can be prematurely induced by oxidative stress involved in aging. In this work, we were searching for novel intermediaries in oxidative stress-induced senescence, focusing our interest on integrin-linked kinase (ILK), a scaffold protein at cell-extracellular matrix (ECM) adhesion...

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Publicat a:Oxid Med Cell Longev
Autors principals: Troyano-Suárez, Nuria, del Nogal-Avila, María, Mora, Inés, Sosa, Patricia, López-Ongil, Susana, Rodriguez-Puyol, Diego, Olmos, Gemma, Ruíz-Torres, María Piedad
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637093/
https://ncbi.nlm.nih.gov/pubmed/26583057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/416738
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