Glucose Oxidase Induces Cellular Senescence in Immortal Renal Cells through ILK by Downregulating Klotho Gene Expression

Cellular senescence can be prematurely induced by oxidative stress involved in aging. In this work, we were searching for novel intermediaries in oxidative stress-induced senescence, focusing our interest on integrin-linked kinase (ILK), a scaffold protein at cell-extracellular matrix (ECM) adhesion...

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Bibliografiske detaljer
Udgivet i:Oxid Med Cell Longev
Main Authors: Troyano-Suárez, Nuria, del Nogal-Avila, María, Mora, Inés, Sosa, Patricia, López-Ongil, Susana, Rodriguez-Puyol, Diego, Olmos, Gemma, Ruíz-Torres, María Piedad
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637093/
https://ncbi.nlm.nih.gov/pubmed/26583057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/416738
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