PI3K/AKT/mTOR/p70S6K Pathway Is Involved in Aβ25-35-Induced Autophagy

Disruption or deregulation of the autophagy system has been implicated in neurodegenerative disorders such as Alzheimer's disease (AD). Aβ plays an important role in this autophagic system. In many cases, autophagy is regulated by the phosphatidylinositol 3-phosphate kinase/AKT/mammalian target...

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Dades bibliogràfiques
Publicat a:Biomed Res Int
Autors principals: Fan, Shengnuo, Zhang, Bei, Luan, Ping, Gu, Beibei, Wan, Qing, Huang, Xiaoyun, Liao, Wang, Liu, Jun
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637023/
https://ncbi.nlm.nih.gov/pubmed/26583091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/161020
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