PI3K/AKT/mTOR/p70S6K Pathway Is Involved in Aβ25-35-Induced Autophagy

Disruption or deregulation of the autophagy system has been implicated in neurodegenerative disorders such as Alzheimer's disease (AD). Aβ plays an important role in this autophagic system. In many cases, autophagy is regulated by the phosphatidylinositol 3-phosphate kinase/AKT/mammalian target...

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Bibliografische gegevens
Gepubliceerd in:Biomed Res Int
Hoofdauteurs: Fan, Shengnuo, Zhang, Bei, Luan, Ping, Gu, Beibei, Wan, Qing, Huang, Xiaoyun, Liao, Wang, Liu, Jun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Hindawi Publishing Corporation 2015
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637023/
https://ncbi.nlm.nih.gov/pubmed/26583091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/161020
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