PI3K/AKT/mTOR/p70S6K Pathway Is Involved in Aβ25-35-Induced Autophagy

Disruption or deregulation of the autophagy system has been implicated in neurodegenerative disorders such as Alzheimer's disease (AD). Aβ plays an important role in this autophagic system. In many cases, autophagy is regulated by the phosphatidylinositol 3-phosphate kinase/AKT/mammalian target...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Fan, Shengnuo, Zhang, Bei, Luan, Ping, Gu, Beibei, Wan, Qing, Huang, Xiaoyun, Liao, Wang, Liu, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637023/
https://ncbi.nlm.nih.gov/pubmed/26583091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/161020
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