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COP9 Signalosome Controls the Degradation of Cytosolic Misfolded Proteins and Protects Against Cardiac Proteotoxicity
RATIONALE: Impaired degradation of misfolded proteins is associated with a large subset of heart diseases. Misfolded proteins are degraded primarily by the ubiquitin-proteasome system (UPS) but the ubiquitin ligases responsible for the degradation remain largely unidentified. The cullin deneddylatio...
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| Udgivet i: | Circ Res |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4636927/ https://ncbi.nlm.nih.gov/pubmed/26383969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.115.306783 |
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