On the Adjacency Matrix of RyR2 Cluster Structures

In the heart, electrical stimulation of cardiac myocytes increases the open probability of sarcolemmal voltage-sensitive Ca(2+) channels and flux of Ca(2+) into the cells. This increases Ca(2+) binding to ligand-gated channels known as ryanodine receptors (RyR2). Their openings cause cell-wide relea...

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Udgivet i:PLoS Comput Biol
Main Authors: Walker, Mark A., Kohl, Tobias, Lehnart, Stephan E., Greenstein, Joseph L., Lederer, W. J., Winslow, Raimond L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636394/
https://ncbi.nlm.nih.gov/pubmed/26545234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004521
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