Dexrazoxane Diminishes Doxorubicin-Induced Acute Ovarian Damage and Preserves Ovarian Function and Fecundity in Mice

Advances in cancer treatment utilizing multiple chemotherapies have dramatically increased cancer survivorship. Female cancer survivors treated with doxorubicin (DXR) chemotherapy often suffer from an acute impairment of ovarian function, which can persist as long-term, permanent ovarian insufficien...

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Udgivet i:PLoS One
Main Authors: Kropp, Jenna, Roti Roti, Elon C., Ringelstetter, Ashley, Khatib, Hasan, Abbott, David H., Salih, Sana M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636352/
https://ncbi.nlm.nih.gov/pubmed/26544188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142588
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