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Dexrazoxane Diminishes Doxorubicin-Induced Acute Ovarian Damage and Preserves Ovarian Function and Fecundity in Mice

Advances in cancer treatment utilizing multiple chemotherapies have dramatically increased cancer survivorship. Female cancer survivors treated with doxorubicin (DXR) chemotherapy often suffer from an acute impairment of ovarian function, which can persist as long-term, permanent ovarian insufficien...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kropp, Jenna, Roti Roti, Elon C., Ringelstetter, Ashley, Khatib, Hasan, Abbott, David H., Salih, Sana M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636352/
https://ncbi.nlm.nih.gov/pubmed/26544188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142588
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