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Bortezomib Prevents Acute Doxorubicin Ovarian Insult and Follicle Demise, Improving the Fertility Window and Pup Birth Weight in Mice

Increasing numbers of female patients survive cancer, but succumb to primary ovarian insufficiency after chemotherapy. We tested the hypothesis that Bortezomib (Bort) protects ovaries from doxorubicin (DXR) chemotherapy by treating female mice with Bort 1 hour prior to DXR. By preventing DXR accumul...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Roti Roti, Elon C., Ringelstetter, Ashley K., Kropp, Jenna, Abbott, David H., Salih, Sana M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176970/
https://ncbi.nlm.nih.gov/pubmed/25251158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108174
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