Evolution of Robustness to Protein Mistranslation by Accelerated Protein Turnover

Translational errors occur at high rates, and they influence organism viability and the onset of genetic diseases. To investigate how organisms mitigate the deleterious effects of protein synthesis errors during evolution, a mutant yeast strain was engineered to translate a codon ambiguously (mistra...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS Biol
Egile Nagusiak: Kalapis, Dorottya, Bezerra, Ana R., Farkas, Zoltán, Horvath, Peter, Bódi, Zoltán, Daraba, Andreea, Szamecz, Béla, Gut, Ivo, Bayes, Mónica, Santos, Manuel A. S., Pál, Csaba
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2015
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636289/
https://ncbi.nlm.nih.gov/pubmed/26544557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002291
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