Evolution of Robustness to Protein Mistranslation by Accelerated Protein Turnover

Translational errors occur at high rates, and they influence organism viability and the onset of genetic diseases. To investigate how organisms mitigate the deleterious effects of protein synthesis errors during evolution, a mutant yeast strain was engineered to translate a codon ambiguously (mistra...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS Biol
Päätekijät: Kalapis, Dorottya, Bezerra, Ana R., Farkas, Zoltán, Horvath, Peter, Bódi, Zoltán, Daraba, Andreea, Szamecz, Béla, Gut, Ivo, Bayes, Mónica, Santos, Manuel A. S., Pál, Csaba
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2015
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636289/
https://ncbi.nlm.nih.gov/pubmed/26544557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002291
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