A new TLR2 agonist promotes cross-presentation by mouse and human antigen presenting cells

Cross-presentation is the process by which professional APCs load peptides from an extracellularly derived protein onto class I MHC molecules to trigger a CD8(+) T cell response. The ability to enhance this process is therefore relevant for the development of antitumor and antiviral vaccines. We inv...

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Bibliografiske detaljer
Udgivet i:Hum Vaccin Immunother
Main Authors: Santone, Melissa, Aprea, Susanna, Wu, Tom Y H, Cooke, Michael P, Mbow, M Lamine, Valiante, Nicholas M, Rush, James S, Dougan, Stephanie, Avalos, Ana, Ploegh, Hidde, De Gregorio, Ennio, Buonsanti, Cecilia, D'Oro, Ugo
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635931/
https://ncbi.nlm.nih.gov/pubmed/26024409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2015.1027467
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