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H7N9 T-cell epitopes that mimic human sequences are less immunogenic and may induce Treg-mediated tolerance

Avian-origin H7N9 influenza is a novel influenza A virus (IAV) that emerged in humans in China in 2013. Using immunoinformatics tools, we identified several H7N9 T cell epitopes with T cell receptor (TCR)-facing residues identical to those of multiple epitopes from human proteins. We hypothesized th...

詳細記述

保存先:
書誌詳細
出版年:Hum Vaccin Immunother
主要な著者: Liu, Rui, Moise, Leonard, Tassone, Ryan, Gutierrez, Andres H, Terry, Frances E, Sangare, Kotou, Ardito, Matthew T, Martin, William D, De Groot, Anne S
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635734/
https://ncbi.nlm.nih.gov/pubmed/26090577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2015.1052197
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