A Method for Individualizing the Prediction of Immunogenicity of Protein Vaccines and Biologic Therapeutics: Individualized T Cell Epitope Measure (iTEM)

The promise of pharmacogenomics depends on advancing predictive medicine. To address this need in the area of immunology, we developed the individualized T cell epitope measure (iTEM) tool to estimate an individual's T cell response to a protein antigen based on HLA binding predictions. In this...

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Autors principals: Cohen, Tobias, Moise, Leonard, Ardito, Matthew, Martin, William, De Groot, Anne S.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2010
Matèries:
Methodology Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914454/
https://ncbi.nlm.nih.gov/pubmed/20706613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/961752
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